In vivo fluorescence kinetics and photodynamic therapy using 5-aminolaevulinic acid-induced porphyrin: increased damage after multiple irradiations.

Abstract

The kinetics of fluorescence in tumour (TT) and subcutaneous tissue (ST) and the vascular effects of photodynamic therapy (PDT) were studied using protoporphyrin IX (PpIX), endogenously generated after i.v. administration of 100 and 200 mg kg-1 5-aminolaevulinic acid (ALA). The experimental model was a rat skinfold observation chamber containing a thin… (More)
DOI: 10.1038/bjc.1994.412

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@article{Veen1994InVF, title={In vivo fluorescence kinetics and photodynamic therapy using 5-aminolaevulinic acid-induced porphyrin: increased damage after multiple irradiations.}, author={N. M. van der Veen and H. L. van Leengoed and W. M. Star}, journal={British Journal of Cancer}, year={1994}, volume={70}, pages={867 - 872} }