In vivo expansion of the mammary stem/ progenitor cell population by xanthosine infusion.

@article{Capuco2009InVE,
  title={In vivo expansion of the mammary stem/ progenitor cell population by xanthosine infusion.},
  author={Anthony V. Capuco and Christina M. Evock-Clover and Andrea Minuti and David L. Wood},
  journal={Experimental biology and medicine},
  year={2009},
  volume={234 4},
  pages={475-82}
}
Mammary stem cells provide for growth and maintenance of the mammary gland and are therefore of considerable interest as determinants of productivity and efficiency of dairy animals and as targets of carcinogenesis in humans. Xanthosine treatment was previously shown to promote expansion of hepatic stem cells in vitro. The objective of this study was to determine if in vivo treatment with xanthosine can increase the mammary stem cell population. Xanthosine was infused into the right mammary… CONTINUE READING