In vivo evaluation of the inhibitory capacity of human plasma on exogenous surfactant function

@article{Lachmann1994InVE,
  title={In vivo evaluation of the inhibitory capacity of human plasma on exogenous surfactant function},
  author={Prof. Dr. Dr. B. Lachmann and E. P. Eijking and Ka Lun So and Diederik A. M. P. J. Gommers},
  journal={Intensive Care Medicine},
  year={1994},
  volume={20},
  pages={6-11}
}
The adult respiratory distress syndrome (ARDS) and neonatal respiratory distress syndrome (RDS) are characterized by high permeability pulmonary edema which contains plasma-derived proteins inhibiting pulmonary surfactant function. Currently, discussion continues as to what dose of surfactant is required for treatment of these syndromes. The purpose of this study was to investigate the amount of exogenous surfactant needed to overcome the inhibitory components in human plasma. Male adult rats… CONTINUE READING

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