In vivo evaluation of cerebral transplantation of resovist-labeled bone marrow stromal cells in Parkinson's disease rats using magnetic resonance imaging.

@article{Guo2011InVE,
  title={In vivo evaluation of cerebral transplantation of resovist-labeled bone marrow stromal cells in Parkinson's disease rats using magnetic resonance imaging.},
  author={Jing Guo and Jun-kang Shen and Lan Wang and Li Xiao and Rong-jun Zhang and Wei-feng Luo and Zhi-gang Gong and Jing Sun and Han Xu and Pierre Sirois and Kai Li},
  journal={Applied biochemistry and biotechnology},
  year={2011},
  volume={163 5},
  pages={636-48}
}
The effectiveness of Resovist-labeled bone marrow stem cells (BMSCs) was evaluated in vivo following their cerebral transplantation in a model of Parkinson's disease (PD) in rats using MRI, and the MRI findings were further compared with the behavior and histopathological manifestations of these rats. Forty PD rats were randomly assigned into five groups according to the cell doses injected into the rat brain site: control group (normal saline injection) and groups injected with 1 × 10(5), 1.5… CONTINUE READING
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