In-vivo efficacy of toltrazuril on experimentally induced Toxoplasma gondii tissue cysts in lambs: a novel strategy for prevention of human exposure to meat-borne toxoplasmosis.

@article{Kul2013InvivoEO,
  title={In-vivo efficacy of toltrazuril on experimentally induced Toxoplasma gondii tissue cysts in lambs: a novel strategy for prevention of human exposure to meat-borne toxoplasmosis.},
  author={Oğuz Kul and Kader Yildiz and Naci Ocal and Alvaro Freyre and Abdulkerim Deniz and Siyami Karahan and Hasan Tarik Atmaca and Sami Gokpinar and Gungor Cagdas Dincel and Tuba Uzunalioğlu and Osman Safa Terzi},
  journal={Research in veterinary science},
  year={2013},
  volume={94 2},
  pages={269-76}
}
The aim of the present study was to investigate in vivo efficacy of toltrazuril on Toxoplasma gondii tissue cysts following induction of chronic toxoplasmosis in 4-week-old lambs (n=27) by inoculation of 1×10(5) T. gondii ME 49 strain oocysts (day 0). Beginning at the 15th day after inoculation, lambs in Group T20 and Group T40 were given toltrazuril orally 2 times, once every week (Baycox 5%, Bayer Animal Health) at a dose of 20 mg/kg and 40 mg/kg, respectively. Positive control (PC) lambs… CONTINUE READING
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