In vivo efficacy of ceftaroline fosamil in a methicillin-resistant panton-valentine leukocidin-producing Staphylococcus aureus rabbit pneumonia model.

Abstract

Ceftaroline, the active metabolite of the prodrug ceftaroline fosamil, is a cephalosporin with broad-spectrum in vitro activity against Gram-positive organisms, including methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Streptococcus pneumoniae (MDRSP), and common Gram-negative pathogens. This study investigated the in vivo… (More)
DOI: 10.1128/AAC.01707-13

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@article{CroisierBertin2014InVE, title={In vivo efficacy of ceftaroline fosamil in a methicillin-resistant panton-valentine leukocidin-producing Staphylococcus aureus rabbit pneumonia model.}, author={Delphine Croisier-Bertin and Davy Hayez and Sonia Leite da Silva and Delphine Labrousse and Donald P Biek and C{\'e}dric Badiou and Oana Dumitrescu and Pascal Guerard and Pierre-Emmanuel Charles and Lionel Piroth and G{\'e}rard Lina and François Vandenesch and Pascal Chavanet}, journal={Antimicrobial agents and chemotherapy}, year={2014}, volume={58 4}, pages={1855-61} }