In vivo effects of gamma-aminobutyric acid on the urinary bladder contraction accompanying micturition.

Abstract

We studied the effects of the gamma-aminobutyric acid (GABA) receptor agonists, diazepam and muscimol, on the urinary bladder contraction induced by infusion of Tyrode's solution into the bladder in anesthetized rats. Diazepam (1 mg/kg, i.p.) completely inhibited bladder contraction, causing the bladder pressure to rise until solution leaked from the penis… (More)

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@article{Kontani1987InVE, title={In vivo effects of gamma-aminobutyric acid on the urinary bladder contraction accompanying micturition.}, author={Hitoshi Kontani and Yoshinari Kawabata and Ryozo Koshiura}, journal={Japanese journal of pharmacology}, year={1987}, volume={45 1}, pages={45-53} }