In vivo effects of LR5182, cis-3-(3,4-dichlorophenyl)-2-N,N-dimethylaminomethyl-bicyclo-[2,2,2]-octane hydrochloride, an inhibitor of uptake into dopamine and norepinephrine neurons
@article{Fuller1979InVE, title={In vivo effects of LR5182, cis-3-(3,4-dichlorophenyl)-2-N,N-dimethylaminomethyl-bicyclo-[2,2,2]-octane hydrochloride, an inhibitor of uptake into dopamine and norepinephrine neurons}, author={Ray W. Fuller and Kenneth W. Perry and Harold D. Snoddy}, journal={Neuropharmacology}, year={1979}, volume={18}, pages={497-501} }
3 Citations
Effects of antidepressant drugs on dopamine uptake and metabolism
- Psychology, BiologyThe Journal of pharmacy and pharmacology
- 1982
The acute effects on D A and NA uptake in vivo and on DA metabolism are reported and the effects of some classical antidepressants and more recently developed drugs on aspects of dopaminergic function under identical conditions are compared.
Amfonelic acid antagonism of dopamine and norepinephrine depletion by alpha-methyl-m-tyrosine in rat brain.
- BiologyBiochemical pharmacology
- 1981
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In terms of potency, protriptyline proved to be the most active antagonist of the several agents studied, both in terms of preventing catecholamine depletion and antagonizing the neuron blocking action of guanethidine.
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Indomethacin PPP, a PG antagonist, enhanced the responses about 15 to 30% and did not show any antagonistic effects, and it is concluded that the transmitter substance of non-adrenergic inhibitory neurons is neither ATP nor PGs.
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