In vivo effect of Schisandrin B on cytochrome P450 enzyme activity.

Abstract

To investigate the possible drug interaction, this study is designed to evaluate the ability of Schisandrin B (Sch B) to modulate cytochrome P450 3A activity (CYP3A) in vivo and to alter the pharmacokinetic profiles of CYP3A substrate (midazolam) in treated rats. Rats were repeated administered with physiological saline (negative control group… (More)
DOI: 10.1016/j.phymed.2013.02.005

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@article{Li2013InVE, title={In vivo effect of Schisandrin B on cytochrome P450 enzyme activity.}, author={Wei-liang Li and Hua-wen Xin and Ai-rong Yu and Xiao-chun Wu}, journal={Phytomedicine : international journal of phytotherapy and phytopharmacology}, year={2013}, volume={20 8-9}, pages={760-5} }