In vivo dynamics of the 103N mutation following the withdrawal of non-nucleoside reverse transcriptase inhibitors in HIV-infected patients: preliminary results.

@article{Gianotti2004InVD,
  title={In vivo dynamics of the 103N mutation following the withdrawal of non-nucleoside reverse transcriptase inhibitors in HIV-infected patients: preliminary results.},
  author={Nicola Gianotti and Enzo Boeri and Myriam Maillard and Giuseppe Serra and Deborah Ratti and Giulia Gallotta and Daniela Vacchini and Ylenia Tremolada and Antonella Castagna},
  journal={The new microbiologica},
  year={2004},
  volume={27 2 Suppl 1},
  pages={111-7}
}
Due to the preferential selection of the fittest HIV mutants, drug-resistant variants are often overgrown by wild-type virus after treatment interruption. Our objective was to investigate the dynamics of the 103N mutation (which usually does not reduce HIV fitness) following the withdrawal of non-nucleoside reverse transcriptase inhibitors (NNRTIs… CONTINUE READING