In vivo dynamics of chromatin-associated complex formation in mammalian nucleotide excision repair.

@article{Mon2004InVD,
  title={In vivo dynamics of chromatin-associated complex formation in mammalian nucleotide excision repair.},
  author={Martijn J. Mon{\'e} and Tytus Bernaś and Christoffel Dinant and Feliks A Goedvree and Erik M. M. Manders and Marcel Volker and Adriaan B. Houtsmuller and Jan H. J. Hoeijmakers and Wim Vermeulen and Roel van Driel},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 45},
  pages={15933-7}
}
Chromatin is the substrate for many processes in the cell nucleus, including transcription, replication, and various DNA repair systems, all of which require the formation of multiprotein machineries on the chromatin fiber. We have analyzed the kinetics of in vivo assembly of the protein complex that is responsible for nucleotide excision repair (NER) in mammalian cells. Assembly is initiated by UV irradiation of a small area of the cell nucleus, after which the accumulation of GFP-tagged NER… CONTINUE READING
29 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

Similar Papers

Loading similar papers…