In vivo dual-modality photoacoustic and optical coherence tomography imaging of human dermatological pathologies.

Abstract

Vascular abnormalities serve as a key indicator for many skin diseases. Currently available methods in dermatology such as histopathology and dermatoscopy analyze underlying vasculature in human skin but are either invasive, time-consuming, and laborious or incapable of providing 3D images. In this work, we applied for the first time dual-modality photoacoustic and optical coherence tomography that provides complementary information about tissue morphology and vasculature of patients with different types of dermatitis. Its noninvasiveness and relatively short imaging time and the wide range of diseases that it can detect prove the merits of the dual-modality imaging system and show the great potential of its clinical use in the future.

DOI: 10.1364/BOE.6.003163
020040020162017
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@article{Zabihian2015InVD, title={In vivo dual-modality photoacoustic and optical coherence tomography imaging of human dermatological pathologies.}, author={Behrooz Zabihian and Jessika Weingast and Mengyang Liu and Edward Zhang and Paul C. Beard and Hubert Pehamberger and Wolfgang Drexler and Boris Hermann}, journal={Biomedical optics express}, year={2015}, volume={6 9}, pages={3163-78} }