In vivo dosimetry based on SPECT and MR imaging of 166Ho-microspheres for treatment of liver malignancies.

@article{Smits2013InVD,
  title={In vivo dosimetry based on SPECT and MR imaging of 166Ho-microspheres for treatment of liver malignancies.},
  author={Maarten L. J. Smits and Mattijs Elschot and Maurice A.A.J. van den Bosch and Gerrit H. van de Maat and Alfred D. van het Schip and Bernard A Zonnenberg and Peter R. Seevinck and Helena M Verkooijen and Chris JG Bakker and H W de Jong and Marnix Geh Lam and Johannes Franciscus Wil Nijsen},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2013},
  volume={54 12},
  pages={
          2093-100
        }
}
UNLABELLED (166)Ho-poly(l-lactic acid) microspheres allow for quantitative imaging with MR imaging or SPECT for microsphere biodistribution assessment after radioembolization. The purpose of this study was to evaluate SPECT- and MR imaging-based dosimetry in the first patients treated with (166)Ho radioembolization. METHODS Fifteen patients with unresectable, chemorefractory liver metastases of any origin were enrolled in this phase 1 study and were treated with (166)Ho radioembolization… CONTINUE READING
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