In vivo detection of somatostatin receptors in patients with functionless pituitary adenomas by means of a radioiodinated analog of somatostatin ([123I]SDZ 204-090).

@article{Faglia1991InVD,
  title={In vivo detection of somatostatin receptors in patients with functionless pituitary adenomas by means of a radioiodinated analog of somatostatin ([123I]SDZ 204-090).},
  author={Giovanni Faglia and N Bazzoni and Anna Spada and Maura Arosio and Bruno Ambrosi and Francesco Spinelli and Roberto Sara and Chiara Bonino and Francesca Lunghi},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1991},
  volume={73 4},
  pages={850-6}
}
The recent availability of a Tyr3-substituted octreotide (SDZ 204-090) for radioiodination has allowed somatostatin (SRIH) receptor binding to be studied in vivo, and receptor-positive tumors of different origins to be visualized with a gamma-camera. This prompted us to investigate whether this compound could be used for external imaging of functionless pituitary adenomas displaying SRIH receptors. Eight patients with functionless pituitary adenomas, three patients with acromegaly, and three… CONTINUE READING
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