In vivo demonstration and quantification of intracellular Bacillus anthracis in lung epithelial cells.

@article{Russell2008InVD,
  title={In vivo demonstration and quantification of intracellular Bacillus anthracis in lung epithelial cells.},
  author={Brooke H. Russell and Qing Liu and Sarah A. Jenkins and Michael J. Tuvim and Burton F Dickey and Yi Xu},
  journal={Infection and immunity},
  year={2008},
  volume={76 9},
  pages={3975-83}
}
Inhalational anthrax is initiated by the entry of Bacillus anthracis spores into the lung. A critical early event in the establishment of an infection is the dissemination of spores from the lung. Using in vitro cell culture assays, we previously demonstrated that B. anthracis spores are capable of entering into epithelial cells of the lung and crossing a barrier of lung epithelial cells without apparent disruption of the barrier integrity, suggesting a novel portal for spores to disseminate… CONTINUE READING

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