In vivo contribution of murine mesenchymal stem cells into multiple cell-types under minimal damage conditions.

@article{AnjosAfonso2004InVC,
  title={In vivo contribution of murine mesenchymal stem cells into multiple cell-types under minimal damage conditions.},
  author={Fernando Anjos-Afonso and Elena Konstantina Siapati and Dominique Bonnet},
  journal={Journal of cell science},
  year={2004},
  volume={117 Pt 23},
  pages={5655-64}
}
Murine mesenchymal stem cells are capable of differentiating in vitro into different lineages under stimulation with certain cytokines, growth factors and chemicals. However, the true capacity of these cells to contribute to different cell-types in vivo is still unclear, especially under minimal injury conditions. In this study, we describe a method of purifying murine mesenchymal stem cells from bone marrow and efficiently transducing them using a lentivirus vector expressing the eGFP reporter… CONTINUE READING