In vivo confocal laser laparoscopy allows real time subsurface microscopy in animal models of liver disease.

@article{Goetz2008InVC,
  title={In vivo confocal laser laparoscopy allows real time subsurface microscopy in animal models of liver disease.},
  author={Martin Goetz and Michael Vieth and Stephan Kanzler and Peter Robert Galle and Peter G. Delaney and Markus F Neurath and Ralf Kiesslich},
  journal={Journal of hepatology},
  year={2008},
  volume={48 1},
  pages={91-7}
}
BACKGROUND/AIMS Histopathology is essential in the diagnostic workup of most liver diseases. However, biopsy sampling might carry risks, is subject to sampling error, and does not provide dynamic tissue imaging. Therefore a newly developed miniaturised confocal probe was evaluated for in vivo microscopic imaging in rodent models of human liver diseases. METHODS The handheld laparoscopy probe used a 488nm single line laser for fluorophore excitation. Optical slice thickness was 7 microm… CONTINUE READING

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