In vivo cleavage specificity of Trypanosoma brucei editosome endonucleases

@inproceedings{Carnes2017InV,
  title={
In vivo cleavage specificity of Trypanosoma brucei editosome endonucleases},
  author={Jason Carnes and Suzanne M McDermott and Atashi Anupama and Brian G G Oliver and D Noah Sather and Kenneth D. Stuart},
  booktitle={Nucleic acids research},
  year={2017}
}
RNA editing is an essential post-transcriptional process that creates functional mitochondrial mRNAs in Kinetoplastids. Multiprotein editosomes catalyze pre-mRNA cleavage, uridine (U) insertion or deletion, and ligation as specified by guide RNAs. Three functionally and compositionally distinct editosomes differ by the mutually exclusive presence of the KREN1, KREN2 or KREN3 endonuclease and their associated partner proteins. Because endonuclease cleavage is a likely point of regulation for RNA… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 5 times over the past 90 days. VIEW TWEETS

References

Publications referenced by this paper.
Showing 1-10 of 47 references

Similar Papers

Loading similar papers…