In vivo cisplatin resistance of rat ascites hepatoma AH66.

@article{Minamino1996InVC,
  title={In vivo cisplatin resistance of rat ascites hepatoma AH66.},
  author={Tetsuo Minamino and Masaya Nomura and Mitsuo Tamai and Shuzo Moritani and Takayuki Ohshima and Ken-Ichi Miyamoto},
  journal={Cancer letters},
  year={1996},
  volume={108 2},
  pages={153-6}
}
The rat ascites hepatoma AH66 cell line had higher resistance to cisplatin than a variant AH66F cell line in in vivo experiments, though in vitro sensitivities to cisplatin of both cell lines were similar in a medium containing 5% fetal calf serum (FCS). When AH cells were cultured in the medium containing 5% ascites fluid (ASF), the sensitivity of AH66… CONTINUE READING