# In vivo characterization of protein uptake by yeast cell envelope: single cell AFM imaging and μ-tip-enhanced Raman scattering study.

@article{Naumenko2013InVC,
title={In vivo characterization of protein uptake by yeast cell envelope: single cell AFM imaging and $\mu$-tip-enhanced Raman scattering study.},
author={Denys Naumenko and Valentinas Snitka and Elena Servienė and Ingrida Bruzaite and Boris Snopok},
journal={The Analyst},
year={2013},
volume={138 18},
pages={
5371-83
}
}
Direct detection of biological transformations of single living cells in vivo has been performed by the advanced combination of local topographic imaging by Atomic Force Microscopy (AFM) and label-free sub-surface chemical characterization using new μ-Tip-Enhanced Raman Spectroscopy (μ-TERS). The enhancing mechanism for μ-TERS tips with micrometre range radius differs significantly to that of the conventional tapered structures terminated by a sharp apex and conditioned by the effects of…
21 Citations

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