In vivo characterization of 5-HT1A receptor-mediated gastric relaxation in conscious dogs.

@article{Janssen2003InVC,
  title={In vivo characterization of 5-HT1A receptor-mediated gastric relaxation in conscious dogs.},
  author={Pieter Janssen and Nicolaas H Prins and B. Moreaux and Ann L. Meulemans and Romain Adelin Lefebvre},
  journal={British journal of pharmacology},
  year={2003},
  volume={140 5},
  pages={913-20}
}
Accumulating data have been published emphasizing the important role of 5-hydroxytryptamine (5-HT) receptors in proximal stomach relaxation. However, a proper in vivo characterization of 5-HT receptors mediating gastric relaxation is still missing. In the current study, we focus on the in vivo characterization of 5-HT1A receptors mediating relaxation of the proximal stomach in conscious dogs. Beagle dogs were equipped with a gastric fistula. In the conscious state, volume changes within an… CONTINUE READING