In vivo changes of heterogeneity of mouse peritoneal macrophages induced by cis-diamminedichloroplatinum (II) (cis-DDP) and related platinum compounds.

Abstract

The s.c. injection of cis-DDP into ABD2F1 mice (8 mg/kg b.m.) resulted in alterations of size and surface structure of peritoneal macrophages (PM) and in a reduction of the mean number of Concanavalin A (ConA) binding sites of PM. The PM population of control mice which received physiological saline only consisted of 2 subgroups with a higher and a lower… (More)

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@article{Peschke1992InVC, title={In vivo changes of heterogeneity of mouse peritoneal macrophages induced by cis-diamminedichloroplatinum (II) (cis-DDP) and related platinum compounds.}, author={Theo Peschke and Heinz Schr{\"o}er and Kurt Augsten}, journal={Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie}, year={1992}, volume={44 3}, pages={154-9} }