In vivo cartilage tissue engineering using a cell-derived extracellular matrix scaffold.

@article{Jin2007InVC,
  title={In vivo cartilage tissue engineering using a cell-derived extracellular matrix scaffold.},
  author={Cheng Zhe Jin and So Ra Park and Byung Hyune Choi and Kwideok Park and Byoung-hyun Min},
  journal={Artificial organs},
  year={2007},
  volume={31 3},
  pages={183-92}
}
We have observed in our previous study that a cell-derived extracellular matrix (ECM) scaffold could assure the growth of a cartilage tissue construct in vitro. The purpose of the present study was to evaluate the feasibility of a chondrocyte-seeded cell-derived ECM scaffold by implanting it in vivo in nude mouse. A porous cell-derived ECM scaffold was prepared with a freeze-drying protocol using porcine chondrocytes. Rabbit articular chondrocytes were seeded onto the scaffold and cultured for… CONTINUE READING

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