In vivo biological response to highly cross-linked and vitamin e-doped polyethylene--a particle-Induced osteolysis animal study.

@article{Huang2016InVB,
  title={In vivo biological response to highly cross-linked and vitamin e-doped polyethylene--a particle-Induced osteolysis animal study.},
  author={Chang-Hung Huang and Yung-Chang Lu and Ting-Kuo Chang and I-Lin Hsiao and Yi-Ching Su and Shu-ting Yeh and Hsu-Wei Fang and C J Huang},
  journal={Journal of biomedical materials research. Part B, Applied biomaterials},
  year={2016},
  volume={104 3},
  pages={561-7}
}
Polyethylene particle-induced osteolysis is the primary limitation in the long-term success of total joint replacement with conventional ultra high molecular weight polyethylene (UHMWPE). Highly cross-linked polyethylene (HXLPE) and vitamin E-doped cross-linked polyethylene (VE-HXLPE) have been developed to increase the wear resistance of joint surfaces. However, very few studies have reported on the incidence of particle-induced osteolysis for these novel materials. The aim of this study was… CONTINUE READING
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