In vivo bioassay-guided fractionation of marine sediment extracts from the Southern California Bight, USA, for estrogenic activity.

@article{Schlenk2005InVB,
  title={In vivo bioassay-guided fractionation of marine sediment extracts from the Southern California Bight, USA, for estrogenic activity.},
  author={Daniel Schlenk and Yelena Sapozhnikova and Mary Ann Irwin and Lingtian Xie and Wendy Hwang and Sharanya Reddy and Bruce J. Brownawell and Jeff Armstrong and Mike Kelly and David E. Montagne and Edward P. Kolodziej and David Sedlak and Shane Snyder},
  journal={Environmental toxicology and chemistry},
  year={2005},
  volume={24 11},
  pages={2820-6}
}
The exposure and uptake of environmental estrogenic compounds have been reported in previous studies of demersal flatfish species in the central Southern California Bight (SCB), USA. The objective of this study was to evaluate the estrogenic or feminizing activity of marine sediments from the SCB by using in vivo vitellogenin (VTG) assays in male or juvenile fish. In 2003, sediments were collected near wastewater outfalls serving the counties of Los Angeles (LACSD) and Orange (OCSD), and the… CONTINUE READING

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