In-vivo autologous bladder muscular wall regeneration: application of tissue-engineered pericardium in a model of bladder as a bioreactor.

@article{Kajbafzadeh2011InvivoAB,
  title={In-vivo autologous bladder muscular wall regeneration: application of tissue-engineered pericardium in a model of bladder as a bioreactor.},
  author={Abdol-Mohammad Kajbafzadeh and Shadi Abdar Esfahani and Saman Shafaat Talab and Azadeh Elmi and Maryam Monajemzadeh},
  journal={Journal of pediatric urology},
  year={2011},
  volume={7 3},
  pages={317-23}
}
PURPOSE Tissue-engineered pericardium (TEP) is a collagen-rich matrix that has previously been shown to promote in vivo and in vitro tissue regeneration. We evaluated the potential of TEP as a source for the in-vivo creation of bladder muscular wall grafts. We used bladder wall as a bioreactor to create a natural environment for cellular growth and differentiation. MATERIALS AND METHODS Sixteen rabbits were divided into four groups. A control group underwent classical bladder autoaugmentation… CONTINUE READING
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