In vivo assessment of retinal neuronal layers in multiple sclerosis with manual and automated optical coherence tomography segmentation techniques

@article{Seigo2012InVA,
  title={In vivo assessment of retinal neuronal layers in multiple sclerosis with manual and automated optical coherence tomography segmentation techniques},
  author={Michaela A. Seigo and Elias S Sotirchos and Scott D. Newsome and Aleksandra Babiarz and Christopher Eckstein and E’Tona Ford and J. Oakley and Stephanie B. Syc and Teresa C. Frohman and John N. Ratchford and Laura Joan Balcer and Elliot M. Frohman and Peter A. Calabresi and Shiv Saidha},
  journal={Journal of Neurology},
  year={2012},
  volume={259},
  pages={2119-2130}
}
Macular optical coherence tomography (OCT) segmentation, enabling quantification of retinal axonal and neuronal subpopulations, may help elucidate the neuroretinal pathobiology of multiple sclerosis (MS). This study aimed to determine the agreement, reproducibility, and visual correlations of retinal layer thicknesses measured by different OCT segmentation techniques, on two spectral-domain OCT devices. Macular scans of 52 MS patients and 30 healthy controls from Spectralis OCT and Cirrus HD… CONTINUE READING
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Optical coherence tomography as a marker of axonal damage in multiple sclerosis

  • S Saidha, C Eckstein, JN Ratchford
  • CML Mult Scler
  • 2010
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