In vivo assessment of aqueous humor dynamics upon chronic ocular hypertension and hypotensive drug treatment using gadolinium-enhanced MRI.

@article{Ho2014InVA,
  title={In vivo assessment of aqueous humor dynamics upon chronic ocular hypertension and hypotensive drug treatment using gadolinium-enhanced MRI.},
  author={Leon C. Ho and Ian P. Conner and Chi Wai Do and Seong-Gi Kim and Ed. X. Wu and Gadi Wollstein and Joel S. Schuman and Kevin C. Chan},
  journal={Investigative ophthalmology \& visual science},
  year={2014},
  volume={55 6},
  pages={
          3747-57
        }
}
PURPOSE Although glaucoma treatments alter aqueous humor (AH) dynamics to lower intraocular pressure, the regulatory mechanisms of AH circulation and their contributions to the pathogenesis of ocular hypertension and glaucoma remain unclear. We hypothesized that gadolinium-enhanced magnetic resonance imaging (Gd-MRI) can visualize and assess AH dynamics upon sustained intraocular pressure elevation and pharmacologic interventions. METHODS Gadolinium contrast agent was systemically… 

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