In vivo antimutagenic activity of beta-carotene in rat spleen lymphocytes.

@article{Aidoo1995InVA,
  title={In vivo antimutagenic activity of beta-carotene in rat spleen lymphocytes.},
  author={Anane Aidoo and Lascelles E. Lyn-Cook and Shelly Lensing and Michelle E Bishop and Wayne G. Wamer},
  journal={Carcinogenesis},
  year={1995},
  volume={16 9},
  pages={2237-41}
}
The anticarcinogenic effects of beta-carotene (BC) have been extensively investigated, but only in vitro assays have examined the ability of BC to modulate gene mutation. In view of the current interest in the provitamin as a cancer chemopreventive agent, and the association between mutagenesis and carcinogenesis, we have dosed Fischer 344 rats with model carcinogen N-ethyl-N-nitrosourea (ENU) and investigated the relationships among BC intake, its tissue accumulation, and antimutagen activity… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-7 of 7 extracted citations

Similar Papers

Loading similar papers…