In vivo anti-inflammatory effect of a sulfated polysaccharide isolated from the marine brown algae Lobophora variegata.

@article{Siqueira2011InVA,
  title={In vivo anti-inflammatory effect of a sulfated polysaccharide isolated from the marine brown algae Lobophora variegata.},
  author={R{\^o}mmulo Celly Lima Siqueira and Michelle Soares Josino da Silva and Daniel Barroso de Alencar and Alana de Freitas Pires and Nylane Maria Nunes de Alencar and Maria Luiza Gonçalves Pereira and Benildo Sousa Cavada and Alexandre Holanda Sampaio and Wladimir Ronald Lobo Farias and Ana Maria Sampaio Assreuy},
  journal={Pharmaceutical biology},
  year={2011},
  volume={49 2},
  pages={167-74}
}
CONTEXT Lobophora variegata J.V. Lamouroux (Dictyotaceae) is a brown marine alga widely encountered in the Brazilian sea coast that presents high content of fucans. Anti-inflammatory effects of fucans are reported mostly in models in vitro, but little is known about its effects in vivo. OBJECTIVE To investigate vascular and cellular effects of a sulfated polysaccharide from the brown marine algae L. variegata (SP-Lv) in acute inflammatory models. MATERIALS AND METHODS SP-Lv was isolated by… CONTINUE READING
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