In vivo anti-inflammatory activities of novel cytokine IL-38 in Murphy Roths Large (MRL)/lpr mice.


The newly named interleukin (IL)-36 subfamily member IL-38 has been shown to exert anti-inflammatory activity. However, the in vivo immunomodulatory activity of IL-38 was poorly investigated in systemic lupus erythematosus (SLE). We have investigated the expression of CD4+IL-17+ Th17, CD4+IFN-γ+ Th1 and CD3+CD4-CD8- double negative (DN) T cells and the… (More)
DOI: 10.1016/j.imbio.2016.10.012

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