In vivo and protease-activated receptor-1-mediated platelet activation but not response to antiplatelet therapy predict two-year outcomes after peripheral angioplasty with stent implantation.

@article{Gremmel2013InVA,
  title={In vivo and protease-activated receptor-1-mediated platelet activation but not response to antiplatelet therapy predict two-year outcomes after peripheral angioplasty with stent implantation.},
  author={Thomas Gremmel and Sabine Steiner and Daniela Seidinger and Renate Koppensteiner and Simon Panzer and Christoph W. Kopp},
  journal={Thrombosis and haemostasis},
  year={2013},
  volume={111 3},
  pages={
          474-82
        }
}
Data linking the response to antiplatelet therapy with clinical outcomes after angioplasty and stenting for lower extremity artery disease (LEAD) are scarce. Moreover, associations of in vivo and thrombin-inducible platelet activation with the occurrence of adverse events have not been investigated in these patients, so far. We therefore assessed clinical outcomes and on-treatment platelet reactivity by four test systems in 108 patients receiving dual antiplatelet therapy after infrainguinal… CONTINUE READING

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