In vivo and in vitro regulation of syndecan 1 in prostate cells by n-3 polyunsaturated fatty acids.

@article{Edwards2008InVA,
  title={In vivo and in vitro regulation of syndecan 1 in prostate cells by n-3 polyunsaturated fatty acids.},
  author={Iris J. Edwards and Haiguo Sun and Yunping Hu and Isabelle M. Berquin and Joseph T O'flaherty and John Mark Cline and Lawrence Lee Rudel and Yong Q. Chen},
  journal={The Journal of biological chemistry},
  year={2008},
  volume={283 26},
  pages={18441-9}
}
Syndecan 1 is the major proteoglycan produced by epithelial cells. It is strategically localized at the plasma membrane to participate in growth factor signaling and cell-cell and cell-matrix interactions. Its expression may modulate the properties of epithelial lineage tumor cells in which it is generally down-regulated compared with nontumor progenitors. The present study examined the regulation of syndecan 1 in prostate epithelial cells by n-3 polyunsaturated fatty acids. In prostate tissue… CONTINUE READING
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