In vivo and in vitro degradation of glucagon-like peptide-2 in humans.

@article{Hartmann2000InVA,
  title={In vivo and in vitro degradation of glucagon-like peptide-2 in humans.},
  author={Bolette Hartmann and Mette Bj\orndal Harr and Per Bendix Jeppesen and Morten Wojdemann and Carolyn F Deacon and Per Brobech Mortensen and Jens Juul Holst},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2000},
  volume={85 8},
  pages={2884-8}
}
Glucagon-like peptide-2 (GLP-2), an intestinal product of glucagon gene expression which induces intestinal growth in mice, has been proposed as a treatment for intestinal insufficiency. GLP-2 is metabolized extensively by dipeptidyl peptidase IV (DPP-IV) in rats, but less is known about its fate in humans. Therefore, GLP-2 metabolism was investigated in… CONTINUE READING