In vivo and in vitro boosting effects of tuberculin skin tests in guinea-pigs immunized with living BCG or with killed Mycobacterium tuberculosis.


Eight weeks after the onset of immunization with living BCG vaccine or with heat-killed, dried Mycobacterium tuberculosis in paraffin oil (TB), guinea-pigs were skin tested with small doses of tuberculin PPD. Three weeks later the effect of these tests on skin reactions and on lymphocyte transformation (LT) responses of lymph node lymphocytes (LNL) or… (More)


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