In vivo and in vitro antiviral effects of berberine on influenza virus

@article{Wu2011InVA,
  title={In vivo and in vitro antiviral effects of berberine on influenza virus},
  author={Y. Wu and Ji-qian Li and Ye-ji Kim and J. Wu and Q. Wang and Yu Hao},
  journal={Chinese Journal of Integrative Medicine},
  year={2011},
  volume={17},
  pages={444-452}
}
  • Y. Wu, Ji-qian Li, +3 authors Yu Hao
  • Published 2011
  • Biology, Medicine
  • Chinese Journal of Integrative Medicine
ObjectiveTo explore the potential effects of berberine on influenza virus infection both in vitro and in vivo.MethodsIn vitro anti-influenza virus assays were performed by cytopathogenic effect and neuraminidase assays in Madin Darby canine kidney cells. In vivo anti-influenza virus assays were performed on the viral pneumonia model of mice. The numbers of mice that died within day 2 to day 14 postinfection were recorded to calculate the mortality. On days 2, 4, and 6, the viral titers in the… Expand
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