In-vivo and ex-vivo characterization of laser-induced choroidal neovascularization variability in mice

@article{Hoerster2012InvivoAE,
  title={In-vivo and ex-vivo characterization of laser-induced choroidal neovascularization variability in mice},
  author={Robert Hoerster and Philipp Sebastian Muether and Sarah Vierkotten and Susanne Schroeder and Bernd Kirchhof and Sascha Fauser},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
  year={2012},
  volume={250},
  pages={1579-1586}
}
Retinal argon laser coagulation is an established procedure for induction of choroidal neovascularization (CNV) in rodents. This study aimed to evaluate the in-vivo and ex-vivo morphology and variability of laser-induced CNV spots over time. Female C57/Bl/6 mice, 3–6 months of age, were treated with five spots of retinal argon laser coagulation per eye (150 mW, 100 ms, 50 μm). In-vivo fluorescein angiography (FA) and standard high-resolution spectral-domain optical coherence tomography (SD-OCT… CONTINUE READING