In vivo analysis of glial cell phenotypes during a viral demyelinating disease in mice

@article{Godfraind1989InVA,
  title={In vivo analysis of glial cell phenotypes during a viral demyelinating disease in mice},
  author={Catherine Godfraind and Victor L. Jr. Friedrich and Kathryn V. Holmes and Monique Dubois-Dalcq},
  journal={The Journal of Cell Biology},
  year={1989},
  volume={109},
  pages={2405 - 2416}
}
C57 BL/6N mice injected intracranially with the A59 strain of mouse hepatitis virus exhibit extensive viral replication in glial cells of the spinal cord and develop demyelinating lesions followed by virus clearing and remyelination. To study how different glial cell types are affected by the disease process, we combine three-color immunofluorescence labeling with tritiated thymidine autoradiography on 1-micron frozen sections of spinal cord. We use three different glial cell specific… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 28 CITATIONS

Translational machinery in dendrites of hippocampal neurons in culture.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1996
VIEW 2 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

Glioblastoma-induced attraction of endogenous neural precursor cells is associated with improved survival.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2005
VIEW 1 EXCERPT
CITES BACKGROUND

Aberrant growth and differentiation of oligodendrocyte progenitors in neurofibromatosis type 1 mutants.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2003
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 65 REFERENCES

In situ hybridization analysis of myelin gene transcripts in developing mouse spinal cord

C. Jordan, V. Friedrich, Jr., M. Dubois-Dalcq.
  • J. Neurosci. 9:248-257.
  • 1989
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Migration and myelination by adult glial cells: reconstructive analysis of tissue culture experiments.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1986
VIEW 1 EXCERPT
HIGHLY INFLUENTIAL