In vivo analysis of 3-phosphoinositide dynamics during Dictyostelium phagocytosis and chemotaxis.

Abstract

Phagocytosis and chemotaxis are receptor-mediated processes that require extensive rearrangements of the actin cytoskeleton, and are controlled by lipid second messengers such as phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P3] and phosphatidylinositol 3,4-bisphosphate [PtdIns(3,4)P2]. We used a panel of pleckstrin homology (PH) domains with… (More)

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@article{Dormann2004InVA, title={In vivo analysis of 3-phosphoinositide dynamics during Dictyostelium phagocytosis and chemotaxis.}, author={Dirk Dormann and Gerti Weijer and Simon J. Dowler and Cornelis J Weijer}, journal={Journal of cell science}, year={2004}, volume={117 Pt 26}, pages={6497-509} }