In vivo anabolic effect of strontium on trabecular bone was associated with increased osteoblastogenesis of bone marrow stromal cells.

@article{Peng2010InVA,
  title={In vivo anabolic effect of strontium on trabecular bone was associated with increased osteoblastogenesis of bone marrow stromal cells.},
  author={Songlin Peng and X. Sherry Liu and Ting Wang and Zhaoyang Li and Guangqian Zhou and Keith D. K. Luk and Xiangdong Edward Guo and William W. Lu},
  journal={Journal of orthopaedic research : official publication of the Orthopaedic Research Society},
  year={2010},
  volume={28 9},
  pages={1208-14}
}
In vitro studies have demonstrated that strontium (Sr) could increase osteogenic differentiation of bone marrow stromal cells (BMSCs). We investigated the in vivo effect of Sr on BMSCs. Thirty-six female rats were randomly divided into the following groups: sham operated and treated with either vehicle (Sham + Veh) or Sr compound (Sham + Sr) and ovariectomized and treated with either vehicle (OVX + Veh) or Sr compound (OVX + Sr). Vehicle and Sr were orally administrated daily starting… CONTINUE READING

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