• DOI:10.1016/J.YGYNO.2004.06.008
Corpus ID: 37235407

In vivo adenovirus-mediated gene transduction into mouse endometrial glands: a novel tool to model endometrial cancer in the mouse.

@article{Beauparlant2004InVA,
  title={In vivo adenovirus-mediated gene transduction into mouse endometrial glands: a novel tool to model endometrial cancer in the mouse.},
  author={S. Beauparlant and P. Read and A. Di Cristofano},
  journal={Gynecologic oncology},
  year={2004},
  volume={94 3},
  pages={
          713-8
        }
}

S. Beauparlant, P. Read, A. Di Cristofano

Published 2004

Biology, Medicine

Gynecologic oncology

OBJECTIVE The lack of an endometrial epithelium-specific promoter has slowed down the development of technically advanced mouse models of endometrial cancer. The aim of this study was to test whether direct in vivo adenoviral-mediated gene delivery can be used to circumvent this problem. METHODS Adenoviruses expressing the LacZ reporter gene or the Cre recombinase were injected into the left horn of the mouse uterus. Histochemistry and immunohistochemistry were used to detect expression of… CONTINUE READING

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