In vivo Treg suppression assays.

  title={In vivo Treg suppression assays.},
  author={Creg J Workman and Lauren W. Collison and Maria Bettini and M. Radhakrishna Pillai and Jerold E. Rehg and Dario A A Vignali},
  journal={Methods in molecular biology},
To fully examine the functionality of a regulatory T cell (T(reg)) population, one needs to assess their ability to suppress in a variety of in vivo models. We describe five in vivo models that examine the suppressive capacity of T(regs) upon different target cell types. The advantages and disadvantages of each model including resources, time, and technical expertise required to execute each model are also described. 

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