In vivo P-NMR spectroscopy: muscle energy exchange in paramyotonia patients.

@article{LehmannHorn1985InVP,
  title={In vivo P-NMR spectroscopy: muscle energy exchange in paramyotonia patients.},
  author={Frank Lehmann-Horn and Dieter H{\"o}pfel and Reinhardt R{\"u}del and Kenneth S. Ricker and G. K{\"u}ther},
  journal={Muscle & nerve},
  year={1985},
  volume={8 7},
  pages={
          606-10
        }
}
Using phosphorus nuclear magnetic resonance spectroscopy, we studied the muscle metabolism in four patients with paramyotonia congenita as reflected in the PC/Pi and PC/ATP ratios. At normal body temperature, all results were indistinguishable from controls. After cooling to 29 degrees C muscle temperature and a single 2-sec maximum contraction, the forearm muscles were stiff. At this stage, no decrease in the ATP content could be detected. In greater than 50% of the experiments with patients… CONTINUE READING
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