In vivo NIRF and MR dual-modality imaging using glycol chitosan nanoparticles.

@article{Key2012InVN,
  title={In vivo NIRF and MR dual-modality imaging using glycol chitosan nanoparticles.},
  author={Jaehong Key and Christy L Cooper and Ah Young Kim and Deepika Dhawan and Deborah W Knapp and Kwangmeyung Kim and Jae Hyung Park and Kuiwon Choi and Ick Chan Kwon and K. -P. Park and James F. Leary},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={2012},
  volume={163 2},
  pages={249-55}
}
One difficulty of diagnosing and treating cancer is that it is very challenging to detect cancers in the early stages before metastasis occurs. A variety of imaging modalities needs to be used from non-invasive, moderate resolution modalities, such as magnetic resonance imaging (MRI) to very high-resolution (e.g. fluorescence) imaging that can help guide surgeons during a surgical operation. While MRI can have relatively high resolution and deep penetration to visualize soft tissues, low… CONTINUE READING
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