In vivo MR/optical imaging for gastrin releasing peptide receptor of prostate cancer tumor using Gd-TTDA-NP-BN-Cy5.5.

@article{Lin2011InVM,
  title={In vivo MR/optical imaging for gastrin releasing peptide receptor of prostate cancer tumor using Gd-TTDA-NP-BN-Cy5.5.},
  author={Y C Lin and Kasala Dayananda and Chiao-Yun Chen and G Liu and Tsai-Yueh Luo and Hui-Sheng Hsu and Yun-Ming Wang},
  journal={Bioorganic & medicinal chemistry},
  year={2011},
  volume={19 3},
  pages={1085-96}
}
Magnetic resonance imaging (MRI) has become the leading imaging tool for providing fine anatomical and physiology details. Optical imaging is offering a sensitive and specific method for in vivo molecular imaging of targeting molecules. The goal of this study is to design, synthesize, and characterize a new target-specific dual contrast agent for MR and optical imaging. Hence, [Gd(TTDA-NP)(H(2)O)](2-) was prepared and characterized. In addition, an 8-amino acid Bombesin analogue (BN) peptide… CONTINUE READING