In vivo 3D MRI staining of mouse brain after subcutaneous application of MnCl2.

@article{Watanabe2002InV3,
  title={In vivo 3D MRI staining of mouse brain after subcutaneous application of MnCl2.},
  author={Takashi Watanabe and Oliver Natt and Susann Boretius and Jens Frahm and Thomas Michaelis},
  journal={Magnetic resonance in medicine},
  year={2002},
  volume={48 5},
  pages={852-9}
}
Follow-up T(1)-weighted 3D gradient-echo MRI (2.35 T) of murine brain in vivo (N = 5) at 120 microm isotropic resolution revealed spatially distinct signal increases 6-48 hr after subcutaneous application of MnCl(2) (20 mg/kg). The effects result from a shortening of the water proton T(1) relaxation time due to the presence of unchelated paramagnetic Mn(2… CONTINUE READING