In vivo 1H-magnetic resonance spectroscopy study of amygdala-hippocampal and parietal regions in autism.

@article{Page2006InV1,
  title={In vivo 1H-magnetic resonance spectroscopy study of amygdala-hippocampal and parietal regions in autism.},
  author={Lisa A Page and Eileen M. Daly and Nicole Schmitz and Andrew Simmons and Fiona Toal and Quinton Deeley and Fiona Z. Ambery and Grainne M. McAlonan and Kieran C. Murphy and Declan Murphy},
  journal={The American journal of psychiatry},
  year={2006},
  volume={163 12},
  pages={2189-92}
}
OBJECTIVE The neural basis for autistic spectrum disorders is unclear, but abnormalities in the development of limbic areas and of glutamate have been suggested. Proton magnetic resonance spectroscopy ((1)H-MRS) can be used to measure the concentration of brain metabolites. However, the concentration of glutamate/glutamine in brain regions implicated in autistic spectrum disorders has not yet been examined in vivo. METHOD The authors used (1)H-MRS to investigate the neuronal integrity of the… CONTINUE READING
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