In vivo 1H NMR spectroscopy of an intracerebral glioma in the rat.

@article{Rmy1989InV1,
  title={In vivo 1H NMR spectroscopy of an intracerebral glioma in the rat.},
  author={Chantal R{\'e}my and Markus von Kienlin and Savino Lotito and Aurore François and Alim Louis Benabid and Michel D{\'e}corps},
  journal={Magnetic resonance in medicine},
  year={1989},
  volume={9 3},
  pages={395-401}
}
High-resolution 1H surface coil NMR spectroscopy (MRS) was used to evaluate in vivo the cerebral metabolism changes in rat brain induced by a glial tumor growing in situ. Tumor cells (C6 glioma cells) were stereotaxically placed in the right hemisphere superficially. 1H MRS was performed using 5-mm surface coils implanted over the right hemisphere and the water was suppressed using a binomial sequence. As the intracerebral tumor size increased, there was a marked decrease in the N-acetyl… CONTINUE READING