In vivo, in vitro evaluation of linseed mucilage based buccal mucoadhesive microspheres of venlafaxine.


The purpose of the present research work was to extract linseed mucilage, use it as a mucoadhesive agent and to develop mucoadhesive microspheres for buccal delivery with an intention to avoid hepatic first-pass metabolism, by enhancing residence time in the buccal cavity. Linseed mucilage was extracted and used to prepare microspheres with varying… (More)
DOI: 10.3109/10717544.2010.520351


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