In vitro transcription of human T-cell leukemia virus type 1 is RNA polymerase II dependent.

@article{Lenzmeier1997InVT,
  title={In vitro transcription of human T-cell leukemia virus type 1 is RNA polymerase II dependent.},
  author={Brian A. Lenzmeier and Jennifer K. Nyborg},
  journal={Journal of virology},
  year={1997},
  volume={71 3},
  pages={2577-80}
}
The HTLV-1 promoter directs RNA polymerase II transcription of viral genomic RNA in vivo. However, it has been reported that in vitro, a unique RNA polymerase, with characteristics of RNA polymerases II and III, is capable of HTLV-1 transcription (G. Piras, F. Kashanchi, M. F. Radonovich, J. F. Duvall, and J. N. Brady, J. Virol. 68:6170-6179, 1994). To further characterize the polymerase involved in HTLV-1 transcription in vitro, runoff transcription assays were performed with a variety of… CONTINUE READING